Vials labelled “AstraZeneca, Pfizer – Biontech, Johnson&& Johnson, Sputnik V coronavirus illness (COVID-19) vaccine” are seen in this illustration image taken May 2, 2021. REUTERS/Dado Ruvic/Illustration/File PhotoThe following is a roundup of some of the latest scientific studies on the novel coronavirus and efforts to find treatments and vaccines for COVID-19, the disease caused by the virus.Breakthrough infections uncommon, however possibly contagiousAs of April 30, when roughly 101 million Americans had actually been completely immunized versus COVID-19, “advancement” infections had been reported in 0.01% of them, the U.S. Centers for Disease Control and Prevention (CDC) reported on Tuesday. Roughly 27% of breakthrough infections were asymptomatic, while in 2% of cases, clients died. The CDC had hereditary data for virus samples from 555 development infections. Altered versions of the coronavirus, consisting of those first seen in the UK and South Africa, accounted for 64% of the developments. In a different research study published Tuesday on medRxiv ahead of peer evaluation, scientists reported that amongst 20 fully-vaccinated healthcare employees with development COVID-19 cases, all were infected with versions. An earlier study had linked advancement infections with low viral loads, recommending low transmission threats, but “we found lots of samples in our development mate with high viral load,” said coauthor Pavitra Roychoudhury of the University of Washington. “Our work recommends that not all breakthrough infections are at low danger of initiating transmission and, if they did, these infections might cause the ongoing spread of variants of issue, especially in locations with low vaccination rates.” (https://bit.ly/3oONfcI; https://bit.ly/3vnAzMs)Study refutes anti-vaxxers pregnancy, breast milk claimsUnfounded claims by anti-vaccine activists that COVID-19 shots from Pfizer/BioNTech (PFE.N), and Moderna (MRNA.O) will harm the placenta and contaminate breast milk have been refuted by brand-new data. The vaccines provide artificial messenger RNA (mRNA), which advises the body to make proteins that in turn cause antibodies to assault the coronavirus. Anti-vaxxers claim, with no evidence, that mRNA likewise induces antibodies that attack a protein called syncytin-1, which is necessary for the establishing placenta throughout pregnancy. They also declare mRNA from the vaccines ends up in breast milk. When researchers studied blood samples from 15 females who got a minimum of one dosage of the Pfizer/BioNTech vaccine – including 2 pregnant ladies and five who were breastfeeding – they saw coronavirus antibodies but no antibodies against syncytin-1. None of the breastfeeding ladies had vaccine mRNA in their milk, according to a report published Tuesday on medRxiv ahead of peer review. “This small study tells us that it is unlikely that COVID-19 mRNA vaccination will trigger problems in pregnancy or fertility through cross-reacting antibodies versus syncytin-1, or for breastfed infants through breast milk,” the authors said. (https://bit.ly/3oUf2s1)Vaccines appear safe for “long COVID” survivorsCOVID-19 survivors with remaining signs can safely be vaccinated against the coronavirus, a little research study suggests. Researchers tracked 36 people with “long COVID” who had been hospitalized while acutely ill and who later got a minimum of one dosage of either the Pfizer/BioNTech or AstraZeneca (AZN.L) vaccine. Eight months after admission to the health center, and prior to vaccination, participants had at least one lingering symptom and half had at least four symptoms. Prior to vaccination, their quality-of-life was “considerably reduced” from normal, the scientists reported on Monday in Annals of Internal Medicine. One month after vaccination, 71% of their symptoms remained unchanged, 23% of their signs were improved, and 6% of symptoms had aggravated. There was no significant getting worse in quality-of-life or psychological well-being, and results were comparable with both vaccines, scientists reported. The results might reassure individuals with relentless COVID-19 signs that the different types of vaccines developed by Pfizer/BioNTech or AstraZeneca are “not associated with a reduction in lifestyle or worsening of signs,” the researchers said. (https://bit.ly/3yFhpDA)Moderna says vaccine safe, effective in adolescentsModernas COVID-19 vaccine was 100% reliable in a trial involving 3,732 adolescents aged 12-17, without any significant security issues, the business said on Tuesday. Among participants who got 2 dosages, there were no cases of COVID-19 compared to four cases among those who received a placebo. After only one dosage, the vaccine was 93% reliable in this age, Moderna said. Adverse effects were similar to those reported in earlier research studies, including headache, tiredness, body pains and chills. Moderna prepares to send the findings to regulators for emergency usage authorization in June. The U.S. Centers for Disease Control and Prevention (CDC) said on Monday it is monitoring uncommon reports of mild heart swelling after COVID-19 vaccination in adolescents. The CDC said the condition is not taking place at higher rates than would be expected in the general population, so no causal link to the vaccine has been established. Dr. Amesh Adalja of the Johns Hopkins Center for Health Security said even if vaccines turn out to be the cause, it is essential to consider the risk-benefit ratio. “Vaccines are going to unequivocally be far more useful,” surpassing any low threat of myocarditis, he stated. (https://bit.ly/34kxPDm; https://reut.rs/3hRB2T6)Open https://tmsnrt.rs/3c7R3Bl in an external web browser for a Reuters graphic on vaccines in development.Our Standards: The Thomson Reuters Trust Principles.
REUTERS/Dado Ruvic/Illustration/File PhotoThe following is a roundup of some of the newest scientific studies on the novel coronavirus and efforts to find treatments and vaccines for COVID-19, the illness caused by the virus.Breakthrough infections unusual, but possibly contagiousAs of April 30, when approximately 101 million Americans had been totally vaccinated against COVID-19, “breakthrough” infections had actually been reported in 0.01% of them, the U.S. Centers for Disease Control and Prevention (CDC) reported on Tuesday. The results may assure people with persistent COVID-19 symptoms that the different types of vaccines established by Pfizer/BioNTech or AstraZeneca are “not associated with a decrease in quality of life or worsening of signs,” the researchers said. (https://bit.ly/3yFhpDA)Moderna states vaccine safe, reliable in adolescentsModernas COVID-19 vaccine was 100% effective in a trial involving 3,732 adolescents aged 12-17, with no significant security problems, the business stated on Tuesday. After only one dosage, the vaccine was 93% efficient in this age group, Moderna stated. “Vaccines are going to unquestionably be much more helpful,” exceeding any low danger of myocarditis, he said.