Pandemic-Related Stressors Identified in Parkinson’s Disease

When the study stratified for coping methods, the COVID-19 stress factors had a smaller sized result on depressive and stress and anxiety signs in Parkinsons disease patients susceptible to confrontive coping and planful problem resolving, she stated. “Whereas, we observed a bigger impact of these stress factors in individuals who are vulnerable to utilizing distancing or looking for social assistance as coping mechanisms,” Dommershuijsen said.

Lisanne Dommershuijsen, MSc, a PhD candidate and scientist in epidemiology at the Erasmus University Medical Center in Rotterdam, the Netherlands, reported on a cross-sectional study of 833 participants with Parkinsons illness in the PRIME-NL study at the International Congress of Parkinsons Disease and Movement Disorders. The typical age of individuals was 70.2 and 38% were ladies.

Lisanne Dommershuijsen

The researchers also produced a design of a hypothetical 50% decrease in COVID-19 stressors among all study individuals, however the result wasnt clinically pertinent, Dommershuijsen stated. However, in people with advanced Parkinsons illness– that is, with an Movement Disorder Society– Unified Parkinson Disease Rating Scale rating above average– the result was scientifically pertinent in all results.

” We studied targeted theoretical interventions on COVID-19 stress factors in people with Parkinsons disease,” Dommershuijsen stated. “This disruption in typical life caused substantial mental stress in community-dwelling individuals. Individuals with Parkinsons illness may be specifically susceptible to this tension.
” For circumstances, because minimized levels of physical activity have gotten worse symptoms or due to the fact that individuals with Parkinsons frequently have problem with versatile [adjustments] to fast and drastic changes in everyday regimens, such as those introduced by the COVID-19 pandemic, previous research studies discovered that COVID-19 aggravated depression and stress and anxiety signs and lowered lifestyle (QOL) in individuals with Parkinsons illness,” Dommershuijsen stated.
The goal of the study was to determine the most susceptible subgroups in the Parkinsons population and to suggest potential interventions to ameliorate these effects, she stated.

The study focused on 8 various stressors that emerged in the pandemic: access to care, medication and nursing services; loss of social contact; canceled social events; stress or dispute in the house; failure to perform physical activity or relax; and COVID-19 symptoThe results of interest were depression, as determined with the Beck Depression Inventory (BDI); anxiety, as determined with the Spielberger State-Trait Anxiety Inventory (STAI); and QOL, with the Parkinsons Disease Quality of Life Questionnaire. The aggregate resulted in a scale of 0-40, with the mean stressor score in the research study being 9.6, Dommershuijsen stated.

The BDI and STAI ratings for social stressors– loss of social contacts, social occasions canceled and tension or dispute in the house– exceeded those for the so-called care stress factors– problems accessing nursing, care or medication– she stated, although all 8 stress factors yielded greater BDI and STAI ratings throughout the board.
Vulnerable Subgroups
” When we looked at vulnerable subgroups of individuals with Parkinsons disease, we found more noticable associations in between the COVID-19 tension and psychological health in females, in highly educated individuals, and in individuals with sophisticated Parkinsons illness,” Dommershuijsen stated. The effect on women and people with innovative disease is explainable, Dommershuijsen included in an interview; the previous due to the fact that depressive symptoms are more common in women, and the latter because loss of access to care effects mental wellness.
” The finding that social stress factors were more related to stress and anxiety in extremely educated people was unexpected to us, considered that depression in basic is more typical in individuals with a lower education,” she said in an interview. “One previous research study of the general population recommended this may be related to expectations about available resources, however this findings and the possible description warrants even more investigation.”

Editors note: Find the most recent COVID-19 news and assistance in Medscapes Coronavirus Resource Center.
Social distancing and the shutdown of services like occupational and physical treatment because of COVID-19 have actually had an extensive effect on the mental health of people with Parkinsons illness, a team of researchers in the Netherlands reported, but they likewise determined meaningful targets for intervention.

The prospective interventions the research study recognized were telemedicine by means of virtual assessments to ease care stress factors, and virtual assistance groups and online classes to deal with social stressors. “However, a more customized method is required to target tension or dispute in your home, which was the most essential social stressor affecting depression and stress and anxiety signs in our research study,” she said. “Social work can play an essential role here.”

Dr Roy Alcalay

This article initially appeared on, part of the Medscape Professional Network.

Asked to talk about the research study, Roy Alcalay, MD, teacher of neurology at Columbia University Irving Medical Center in New York, stated in an interview that the findings line up with his research on the impact of COVID-19 and associated limitations on individuals with Parkinsons illness.

” The pandemic has affected people in various methods,” he said. Alcalay authored 2 current papers on the impact of COVID-19 in individuals with Parkinsons disease.

” We studied targeted theoretical interventions on COVID-19 stressors in individuals with Parkinsons illness,” Dommershuijsen stated. People with Parkinsons illness may be especially vulnerable to this stress.
” The pandemic has actually affected individuals in various ways,” he said. “Initially very acutely, individuals simply didnt have access to medical professionals. Alcalay authored 2 current papers on the effect of COVID-19 in individuals with Parkinsons illness.

” Then we see that, in addition to that concern, theres the question of even if they dont have COVID-19, simply the social distancing and the lack of access to healthcare, and particularly to occupational and physical therapy and other services, can be rather damaging,” he said.

Neither Dommershuijsen nor Alcalay have any relevant relationships to divulge.

Whats good about the research study, he stated, was that it simply doesnt highlight the problem. “Theyre also highlighting possible solutions, that planful issue resolving and coping strategies can be practical to people.”

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