“This under-the-skin injection is the first approved drug for chronic weight management in adults with general weight problems or obese given that 2014,” the FDA said in a statement Friday.Studies have actually shown the once-a-week injection, called semaglutide, can help individuals lose up to 12% of their body weight over about a half and a year compared to individuals offered a placebo shot, and 15% of their body weight overall.Semaglutide, to be offered under the brand name Wegovy by maker Novo Nordisk, affects a hormone called glucagon-like peptide-1 and increases the production of insulin. Diabetes clients who checked the drug lost 6.2% more of their body weight compared to individuals who got dummy injections.The trial revealed individuals using Wegovy lost 14.9% of their body weight after about 16 months compared to those offered placebo shots, who lost 2.4% of their body weight. They include orlistat, sold under the brand name Xenical, which helps decrease the quantity of fat the body soaks up; Qsymia, a drug that combines the cravings reducer phentermine with the seizure drug topiramate; Contrave, which integrates the addiction drug naltrexone with the antidepressant bupropion; and liraglutide or Saxenda, a diabetes drug that is comparable to semaglutide.The drug can have side results, including an inflammation of the pancreas, increased heart rate, nausea, diarrhea and ideas of suicide.
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