Van Breemen hopes this trend seen in his findings will apply to other existing and future COVID-19 versions.
Hemp, part of the species Cannabis sativa, is one of the marijuana species grown for industrial and medical use, consisting of in dietary supplements, animal feed, and cosmetics.
Van Breemen states these substances can be taken orally. To him, they have the potential to treat and prevent infection by SARS-CoV-2.
” CBDA and CBGA are produced by the hemp plant as precursors to CBD and CBG, which recognize to numerous customers. They are different from the acids and are not contained in hemp items,” van Breeman noted.
In the research study, these acids had the ability to bind to the SARS-CoV-2 spike protein– the same target utilized in COVID-19 vaccines and antibody treatment. Once bound, this action could block a critical step in the pathogen process used to infect the cell.
The research was conducted at Oregon State University and led by Richard van Breemen, a scientist with Oregon States Global Hemp Innovation Center, College of Pharmacy, and Linus Pauling Institute.
” That indicates cell entry inhibitors, like the acids from hemp, could be utilized to prevent SARS-CoV-2 infection and also to shorten infections by avoiding virus particles from contaminating human cells. They bind to the spike proteins so those proteins cant bind to the ACE2 enzyme, which is abundant on the external membrane of endothelial cells in the lungs and other organs,” said van Breemen in a statement.
The study recommends two compounds discovered in frequently found in hemp– cannabigerolic and cannabidiolic acid– avoid coronavirus from entering cells that usually line internal organs and skin in a lab setting.
Both marijuana substances were discovered equally reliable versus the SARS-CoV-2 alpha and beta variations.
A few of the compounds in marijuana might prevent the entry of the coronavirus into healthy human cells, according to a research study published in the Journal of Nature Products..